For those of you who don't know me very well, I'm a big advocate of accessibility for web applications. Accessibility is so important -- not just because it provides friendly access to applications for those who are disabled, but because the same techniques employed to enable screen-readers to manage web content often work well for allowing search engines or alternative devices to read content.
If you're using AJAX on your web project, you may or may not be aware of the accessability challenges that this design paradigm poses. Bertland Le Roy has an easy-to-implement addition to the ASP.Net AJAX UpdatePanel that makes this powerful control available and accessible to screen readers.
http://dotnetslackers.com/articles/ajax/AccessibleUpdatePanel.aspx